Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Inkscape - Inkscape is a free, open source professional vector graphics editor for Windows, Mac OS X and Linux.
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.
LaTeXDraw - LaTeXDraw is a graphical drawing editor for LaTeX.
Autodesk Maya - Maya is 3D computer animation software with powerful modeling, rendering, simulation, texturing, and animation tools for artists, modelers, and animators.
Ipe - Ipe is a drawing editor for creating figures in PDF or (encapsulated) Postscript format.