Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Sampulator - Make (and record) beats on your keyboard
Autodesk 3DS Max - 3ds Max is software for 3D modeling, animation, rendering, and visualization. Create stunning game enrivonments, design visualizations, and virtual reality experiences.
Auxy Music Studio - Auxy brings real music creation to iPhone in a simple and inspiring format.
ZBrush - ZBrush is a digital sculpting and painting software solution.
Ramsophone - A generative art/music machine. (Be sure to refresh!)