Flox is the best thing I know of for articulating binary dependencies (language runtimes, etc.), which is probably the sweet spot for nix anyways at the moment. Flox uses nix for its backend, but has a simple TOML syntax and is properly humble about what it can do -- but killer at it -- as opposed to promising the world. https://flox.dev. - Source: Hacker News / about 1 month ago

Nix and NixOS are in something like the state git was in before GitHub: the fundamental idea is based on more serious computer science than the status quo (SVN, Docker), the plumbing still has some issues but isn’t worse, and the porcelain and docs are just not there for mainstream adoption. I think that might have changed with the release of flox: https://flox.dev, it’s basically seamless (and that’s not... - Source: Hacker News / 4 months ago

Brew & macports have libvirt & virt-manager that are used to manage qemu via GUI. Source: over 1 year ago

Or instead of all this, try MacPorts[0], which in my experience has 99% of what you need. The biggest drawbacks are less support from quite niche packages (the ones that sets up its own homebrew tap), and a bit slower updates. But then I found it bearable much more than homebrew’s downsides. [0]: https://macports.org. - Source: Hacker News / almost 2 years ago

You can install wireguard-go and wireguard-tools (or boringtun, which is Cloudflare's userspace implementation) using either MacPorts or Brew. Source: almost 2 years ago

That being said, I'm going to assume that you're working on MacO. Flatpaks aren't going to be an option, that's only going to work if you're using Linux (like Fedora, Ubuntu, Gentoo, Arch, Mint, and so on). If you need to install HandBrake, you may want to consider using macports.org, or brew.sh, these are projects that provide additional libraries and packages for MacOS, this way you can install additional... Source: about 2 years ago

On macOS you can also install the latest release with MacPorts:. - Source: dev.to / over 2 years ago