Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.
Listenbox - Podcasts from audio & video on the web
ioBroker - flexible and modular application for the IoT and Smarthome
Audioship - Upload audio to YouTube or Facebook
openHAB - "empowering the smart home" - vendor and technology agnostic open source home automation
TunesToTube - What does TunesToTube do?