Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Game Character Hub - helper program for game design (RPG Maker XP/VX and more)
Sculptris - Sculptris: Enter a world of digital art without barriers.
RPG Character Builder - Create thousands of unique character sprites for your 2D game project - free!
ShapeShop - ShapeShop is an advanced and professional 3D design and modeling application that comes with an easy-to-use and user-friendly interface.
Universal LPC Spritesheet Character Generator - Powerful, animated character generator for creating 2D spritesheets