Monica - Monica is an open-source personal CRM to keep track of your friends and family.
Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.
Algo by ChatBotKit - Your Personal AI Assistent
ioBroker - flexible and modular application for the IoT and Smarthome
Reply Ninja - Instant Inline replies in Gmail
openHAB - "empowering the smart home" - vendor and technology agnostic open source home automation