Thunderbird - Thunderbird is a free email application that's easy to set up and customize - and it's loaded with great features!
Freshdesk - Freshdesk is a cloud-based customer support software that lets you support customers through traditional channels like phone and email, social channels like Facebook and Twitter, and your own branded community
Mailbird - Mailbird is the best email client for Windows 7, 8 and 10
Zoho Desk - Industry's first context-aware Helpdesk Software
Microsoft Outlook - Organize your world. Outlook’s email and calendar tools help you communicate, stay on top of what matters, and get things done.
Salesforce Service Cloud - Service Cloud integrates customer service with social networks and provides a self-service customer portal and knowledge base system.