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PyQt - Riverbank | Software | PyQt | What is PyQt?
Qt - Powerful, flexible and easy to use, Qt will help you not only meet your tight deadline, but also reduce the maintainable code by an astonishing percentage.
Tkinter - Tkinter is a Python wrapper for Tcl/Tk that offers classes to create various graphical user interfaces.
GTK - GTK+ is a multi-platform toolkit for creating graphical user interfaces.
MD Python Designer - A drag and drop GUI Designer that uses a combination of Tkinter and its own code.
wxWidgets - wxWidgets: Cross-Platform GUI Library