Zendesk - Zendesk is a beautiful, lightweight help-desk solution.

Mailtrack.io - The best email tracking solution I've found. Free

Freshdesk - Freshdesk is a cloud-based customer support software that lets you support customers through traditional channels like phone and email, social channels like Facebook and Twitter, and your own branded community

ReadNotify - ReadNotify enables the user to know when email is sent and the reciever reads the email.

HelpScout - Help Scout is a simple, straightforward way to provide excellent support

Bananatag - Find out what happens to your emails after you press send! Add email tracking, attachment tracking, email scheduling and templates to your daily emails.